Raw Material Factory Supply High Quality Nepafenac CAS#78281-72-8

• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Model NO.: CAS#78281-72-8
• Transport Package: 25kg/Drum
• Specification: 42*42*52
• Trademark: Hanways
• Origin: China
• Production Capacity: 2000 Kilogram/Month

Product Description

Nepafenac is a new type of ophthalmic non-steroidal analgesic and anti-inflammatory drugs (NSAIDs) for the treatment of ocular pain and inflammation caused by cataract surgery. Compared with traditional NSAIDs, the chemical book structure of nepafenac facilitates the rapid penetration of the drug into the cornea and its distribution to its target site, thus helping to reduce the accumulation of the drug on the corneal surface and reduce the occurrence of ocular surface complications, with the advantages of strong penetration, strong targeting effect and low toxic side effects.
After ocular administration, nepafenac rapidly crosses the cornea and is converted to amifenacin (an NSAID) by the action of ocular tissue hydrolase; amifenacin, in turn, exerts its anti-inflammatory and analgesic effects by inhibiting prostaglandin H synthase (cyclooxygenase) and blocking prostaglandin synthesis. As it is known, prostaglandins are one of the mediators causing intraocular inflammation, leading to collapse of the blood-atrial water Chemicalbook barrier, vasodilation, increased vascular permeability and leukocyte chemotaxis, etc. In addition, prostaglandins can contract the iris sphincter through a non-cholinergic mechanism, triggering a constricted pupil response during and after ophthalmic surgery. NSAIDs, when administered via the eye, can inhibit NSAIDs, when administered ocularly, inhibit the synthesis of prostaglandins in the iris, ciliary body, and conjunctiva, thus preventing the development of ocular inflammation and reducing associated pain.

Product Name	Nepafenac
Synonyms	AHR 9434;AL 6515;Nevanac;Nepafenac;2-(2-amino-3-benzoyl-phenyl)acetamide;2-Amino-3-benzoylbenzeneacetamide;Nepafenac - WS;nepafenac,Nevance
MOQ	1kg
CAS	78281-72-8
Appearance	faint yellow to dark yellow
Molecular Formula	C15H14N2O2
Molecular Weight	254.28
Assay	>99%
Application	For research purpose only
Packing	25kg/drum
Storage	Store in a well-closed,light-resistant container
Remarks	NA
Custom synthesis	Available